A brother of Erskine Mayer, Sam had only a brief stint as an outfielder for the Washington Senators in 1915. He hit .241 with 1 homer in 37 games. He was fine a defensive outfielder, making many spectacular plays in the minors. But his bat never was good enough to keep him in the big leagues.
Sam pitched to two batters in the seventh inning of a game against the St. Louis Browns on Sept. 17, 1915. He walked both batters.